Fig. 7

tsRNA-16902 is able to bind to the RARγ 3′-UTR. a An analysis of how tsRNA-16902 influenced RARγ expression in the context of hMSC adipogenesis on days 0, 7, and 14. b An illustration of the putative site of tsRNA-16902 binding within the 3′-UTR of RARγ, with green used to highlight those nucleotides mutated for a mutant version of this sequence. c Luciferase activity assay revealed that tsRNA-16902 transfection into cells resulted in a 50% reduction in luciferase activity for constructs containing a WT but not a mutated version of this RARγ 3′-UTR binding site. Data are means ± SD (n = 3). **P < 0.01 vs. negative controls, respectively. Note: NC, negative control; sh, tsRNA-16902 shRNA