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Fig. 3 | Stem Cell Research & Therapy

Fig. 3

From: COCO enhances the efficiency of photoreceptor precursor differentiation in early human embryonic stem cell-derived retinal organoids

Fig. 3

Acceleration of photoreceptor precursor cells after COCO supplement. a Schematic illustration outlining the differentiation protocol to improve precursor cells with COCO. b Fluorescent organoids inducing efficiency supplied by COCO and COCO with IGF1 at different developmental stages. Scale bar, 100 μm. c Fluorescence intensity analysis in D45, D60, D90, and D120 organoids of COCO group (n = 27, 30, 17, 5, respectively) and COCO+IGF1 group (n = 27, 23, 10, 4, respectively) versus control retinal organoids (n = 17, 14, 11, 10, respectively). d Photoreceptor precursor cells between COCO group and control. e Immunohistochemistry with anti-RCVRN antibody on D45 and D60 organoids. Scale bar, 50 μm

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Stem Cell Research & Therapy

ISSN: 1757-6512