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Fig. 6 | Stem Cell Research & Therapy

Fig. 6

From: Aspirin mediates histone methylation that inhibits inflammation-related stemness gene expression to diminish cancer stemness via COX-independent manner

Fig. 6

Aspirin combined HDM (KDM6A/B) or ICAM3 signaling inhibitors restrained cancer progression in vivo. a Schema of the inhibitor therapy model established by subcutaneous implantation of A549-luci cells into the NOD/SCID mice. b The representative luciferase images showing the A549-luci tumors at the primary sites of each group. c Tumor growth curve of A549-luci cells under combination therapy of aspirin and HDM inhibitor, Src/PI3K inhibitors, or Lifitigrast. d The body weight of BALB/c mice inoculated with A549-luci cells under combination therapy of aspirin and HDM inhibitor, Src/PI3K inhibitors, or Lifitigrast. e The survival curve of BALB/c mice inoculated with A549-luci cells under combination therapy of aspirin and HDM inhibitor, Src/PI3K inhibitors, or Lifitigrast

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