Skip to main content
Fig. 5 | Stem Cell Research & Therapy

Fig. 5

From: Overexpressing TGF-β1 in mesenchymal stem cells attenuates organ dysfunction during CLP-induced septic mice by reducing macrophage-driven inflammation

Fig. 5

Effect of MSC-TGF-β1 on the phenotype of LPS-stimulated primary peritoneal macrophages. a, b The MFI of CD86 and CD206 in each group were detected by flow cytometry (n = 3, *p < 0.05 vs. the sham group; #p < 0.05 vs. the CLP group; &p < 0.05 vs. the MSC-NC group). ce The concentrations of IL-6, IL-1β, and IL-10 in macrophages were tested by ELISA (n = 3, *p < 0.05 vs. the sham group; #p < 0.05 vs. the CLP group; &p < 0.05 vs. the MSC-NC group). ELISA, enzyme-linked immunosorbent assay; MFI, mean fluorescence intensity; MSCs, mesenchymal stem cells; MSC-NC, mesenchymal stem cell carrying GFP; MSC-TGF-β1, TGF-β1 overexpressing MSC

Back to article page