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Fig. 7 | Stem Cell Research & Therapy

Fig. 7

From: Facilitating islet transplantation using a three-step approach with mesenchymal stem cells, encapsulation, and pulsed focused ultrasound

Fig. 7

a Representative images following TNF-α immunohistochemical staining and H&E staining of islets that were transplanted under the kidney capsule. Black arrows indicate islets present within the representative images; quantification of b positive TNF-α staining, c inflammatory cell infiltrate; and d the cytokine expression profile in the kidney of mice transplanted with islets (measured with multiplex ELISA) in following tested groups: Islets, e-Islets, m-Islets, em-Islets, and emf-Islets. Significant differences: bd aP < 0.05: Islets vs. e-Islets or m-Islets or em-Islets or emf-Islets; bP < 0.05: e-Islets vs. m-Islets or em-Islets or emf-Islets; cP < 0.05: m-Islets vs. em-Islets or emf-Islets; dP < 0.05: em-Islets vs. emf-Islets (one-way ANOVA post hoc Tukey test)

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