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Fig. 1 | Stem Cell Research & Therapy

Fig. 1

From: A barrier against reactive oxygen species: chitosan/acellular dermal matrix scaffold enhances stem cell retention and improves cutaneous wound healing

Fig. 1

ROS scavenging capacity of the chitosan. a ROS inhibits MSC viability in a dose-dependent manner. b Various chitosan concentrations restore the reduced viability of MSCs in a dose-dependent manner. c Live/dead staining images of the MSCs with H2O2 treatment. Green and red represent lived cells and dead cells, respectively. Scale bars are 200 μm (n = 5). d Images of adhesive cells on culture plastic surface in presence of H2O2. Quantification of adhesive MSCs shows that ROS significantly inhibits the adhesion of MSCs compared to control (untreated with H2O2), while chitosan significantly attenuates the effect induced by ROS. e The measurement of intracellular ROS by DHE staining. Control indicates untreated with H2O2, H2O2 indicates H2O2 treatment, and H2O2+CHS indicates H2O2+chitosan treatment; scale bars are 200 μm; **p < 0.01, *p < 0.05

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