Skip to main content
Fig. 2 | Stem Cell Research & Therapy

Fig. 2

From: RETRACTED ARTICLE: microRNA-375 released from extracellular vesicles of bone marrow mesenchymal stem cells exerts anti-oncogenic effects against cervical cancer

Fig. 2

miR-375 targets MELK gene and suppresses its expression in vitro. a Putative miR-375 binding sites in the 3′UTR of MELK mRNA. b The targeting relationship between miR-375 and MELK verified by dual-luciferase reporter assay in HEK293T cells. c The mRNA protein expression of MELK was determined by RT-qPCR in cervical cancer cell lines after overexpression or inhibition of miR-375, normalized to β-actin. d The protein expression of MELK was determined by Western blot analysis in cervical cancer cell lines after overexpression or inhibition of miR-375, normalized to β-actin. The measurement data are presented as mean ± SD. Two groups of data are compared by an independent sample t test. *p < 0.05 compared with the NC group. The cellular experiment was repeated three times independently

Back to article page