Fig. 2

XF-hMAPC cells induced a mature host vascular network in an in vivo Matrigel implantation assay. a–c Cross-sections stained for mouse (m)CD31 in green and α-smooth muscle-actin (αSMA) in red for the PBS (a; open circles in c; n = 6) or XF-hMAPC cell (“XF”; b; open triangles in c; n = 4) group and the corresponding quantification in c. Data represent the mean fraction of αSMA⁺ vessels expressed as % of CD31⁺ vessels ± S.E.M. (*P < 0.05 versus PBS by unpaired Student’s t test). d–f Cross-sections stained for Sirius red (“S.red”) and photographed in brightfield for the PBS (d; open circles in f; n = 6), or XF-hMAPC (e; open triangles in f; n = 5) group and the corresponding quantification in f. Data represent mean fractional Sirius red⁺ area expressed as % ± S.E.M. (*P < 0.05 versus PBS by unpaired Student’s t test). Panels a, b correspond to panels g, h of Fig. 1. Magnifications at which pictures were taken: × 10 in a, b; × 20 in d, e. Scale bars: 50 μm in a, b; 20 μm in d, e