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Fig. 3 | Stem Cell Research & Therapy

Fig. 3

From: Pulsed focused ultrasound enhances the therapeutic effect of mesenchymal stromal cell-derived extracellular vesicles in acute kidney injury

Fig. 3

Molecular markers of kidney injury. a Immunohistochemical staining showing expression of injury markers KIM-1 and TIMP-1. Scale bar represents 100 μm. b Western blot for KIM-1, NGAL, TIMP-1, and β-actin (left), and their respective quantification (right). c Quantitative real-time PCR for Kim1, Ngal, and Timp1 in the kidney tissue. d ELISA for KIM-1, NGAL, and TIMP-1 measured in the urine. Each group has n = 5 mice. Significant difference ap < 0.05: relative to untreated control; bp < 0.05: relative to AKI; cp < 0.05: relative to AKI-EV; dp < 0.05: relative to AKI-EV-pFUS

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