Skip to main content
Fig. 5 | Stem Cell Research & Therapy

Fig. 5

From: Embryonic stem cell microenvironment enhances proliferation of human retinal pigment epithelium cells by activating the PI3K signaling pathway

Fig. 5

Coculture with ESCs enhances the stem cell phenotype of hRPE cells. a The N:C ratio analysis of hRPE cells. b Colony-forming efficacy and representative images of clones formed by hRPE cells. c Expression of the RPE differentiation markers (CRALBP and PEDF) and stem cell-associated marker (KLF4) in hRPE cells, as assessed by RT-qPCR. c Western blotting of CRALBP and KLF4 in hRPE cells. β-actin served as the internal control. Data are means ± SDs. *P < 0.05; ***P < 0.001; ****P < 0.0001

Back to article page