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Fig. 4 | Stem Cell Research & Therapy

Fig. 4

From: Human menstrual blood-derived stem cells mitigate bleomycin-induced pulmonary fibrosis through anti-apoptosis and anti-inflammatory effects

Fig. 4

MenSC transplantation reduced epithelia cell apoptosis in vivo and repaired the lung structure following fibrosis. a Lung epithelia cell ratio in three different groups (n = 5). b H&E staining and Masson staining of lung sections (n = 5). Scale bar: 50 μm. Severity of pulmonary fibrosis evaluated by modified Ashcroft score (c), fibrosis area (d), and HYP contents (f). e Dry/wet weight ratio analysis (n = 5). g Body weight of mice in three different groups (n = 5). Error bars indicate standard deviation of five biological replicates undergoing independent experiments. *p < 0.05, **p < 0.01, ***p < 0.001 by one way analysis of variance

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