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Fig. 1 | Stem Cell Research & Therapy

Fig. 1

From: Inhibition of hypertrophy and improving chondrocyte differentiation by MMP-13 inhibitor small molecule encapsulated in alginate-chondroitin sulfate-platelet lysate hydrogel

Fig. 1

Mechanical properties of hydrogels with different concentrations of CS. a Compressive stress-strain curve. b Young’s modulus. The results showed higher Young’s modulus in the Alg-CS-1% compared with Alg and Alg-CS-2.5% hydrogels (*, # presented a statistically significant differences compared to Alg-CS-1% with P ≤ 0.01, P ≤ 0.05 respectively). c Rheological measurements. d G′ and G″ calculated at 0.1% strain. The elastic (G′) and viscous (G″) modulus were significantly higher in the Alg-CS-1% hydrogel compared with Alg hydrogels containing CS (0.5, 2.5%). The Alg hydrogels with CS 0.5% and 2.5% had significantly lower G′ and G″ compared with Alg hydrogel (*, # presented a statistically significant difference compared to Alg-CS-1% and Alg hydrogels, respectively (p ≤ 0.001)) (n = 6)

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