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Fig. 3 | Stem Cell Research & Therapy

Fig. 3

From: Inhibition of hypertrophy and improving chondrocyte differentiation by MMP-13 inhibitor small molecule encapsulated in alginate-chondroitin sulfate-platelet lysate hydrogel

Fig. 3

Mechanical properties of different hydrogels with or without cells. a Compressive stress-strain curve. b Young’s modulus calculated from the stress-strain curve. The chart reveals a significantly higher Young’s modulus in the Alg gel containing either both fresh-PL-20% /CS1% or only one of them when compared to Alg hydrogel with or without cells. No significant difference was observed in cell free hydrogels compared with cell containing hydrogels (*, # presented a statistically significant difference compared to other groups in both conditions with or without cells (p ≤ 0.05)). c Rheological measurements of four different hydrogels. d Calculated elastic (G′) and viscous (G″) modulus at 0.1% strain. The results indicated significantly higher G′ and G″ in the Alg-PL hydrogel compared with the other hydrogels (* (p ≤ 0.01), # (p ≤ 0.05)) (n = 3)

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Stem Cell Research & Therapy

ISSN: 1757-6512