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Fig. 7 | Stem Cell Research & Therapy

Fig. 7

From: Inhibition of hypertrophy and improving chondrocyte differentiation by MMP-13 inhibitor small molecule encapsulated in alginate-chondroitin sulfate-platelet lysate hydrogel

Fig. 7

Chondrogenesis assessment in the presence or absence of 39 μM BICA. qRT-PCR was performed to investigate the expression of a Coll II, b ACAN, c MMP-13, d Coll X, e ratio between Coll II and Coll X, f ALP, g Coll I, and h ratio between Coll II and Coll I in four different hydrogels at day 28. Data are presented as means ± SD (n = 3) (*p < 0.05, **p < 0.01, ***p < 0.001)

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