Fig. 7

β-Catenin was a direct target of miR-141-3p, and overexpressing β-catenin boosted proliferation in SAP. a Feasible bind sites of rno-miR-141-5p in β-catenin 3′-UTR. b β-Catenin-wt or β-catenin-mut plasmid was co-transfected with miR-NC or miR-141-3p mimics into 293T cells for 24 h, then luciferase activity was examined. c Relative mRNA expression of β-catenin in MSCs with various treatments detected by qRT-PCR. d–g Western blot analysis of pancreatic β-catenin, c-Myc, and cyclin D1protein levels. Data represent means ± SD from at least three separate experiments. n = 6/group. *p < 0.05, **p < 0.01, ***p < 0.001. NS, not significant