Fig. 1
From: Hepatic stellate cells contribute to liver regeneration through galectins in hepatic stem cell niche
Hepatic stem/progenitor cells are induced following liver injury. a Hepatic oval cells (dotted area) were induced in 2-acetylaminofluorene plus 70% partial hepatectomy (2-AAF/PH)-treated liver (1 week and normal control, H&E stained). b Immunohistochemical co-localization of hepatic stem/progenitor related markers (CK19, OV-6, EpCAM, CD44, and CD133) in normal liver and 2-AAF/PH model liver (1 week). c Dual staining for CK19 and Ki67 at 0, 1, and 2 weeks after 2AAF/PH. d Quantification of c showed a significant elevation of Ki67+ proportion in CK19+ cells (n = 4). Nuclei were stained with DAPI. Scale bar, 100 μm. Data are shown as means ± SD. ***P < 0.001. PV, portal vein; BD, bile duct; HA, hepatic artery; U.D., undetectable