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Fig. 3 | Stem Cell Research & Therapy

Fig. 3

From: UBA2 activates Wnt/β-catenin signaling pathway during protection of R28 retinal precursor cells from hypoxia by extracellular vesicles derived from placental mesenchymal stem cells

Fig. 3

Gene ontology (GO) distribution of differentially expressed proteins in R28 cells damaged by CoCl2 and treated with hPMSC-derived exosomes. a GO annotations for biological processes, molecular functions, and cellular components of upregulated proteins in R28 cells damaged by CoCl2, compared with those of controls. b GO annotations for biological processes, molecular functions, and cellular components of downregulated proteins in R28 cells damaged by CoCl2, compared with those of controls. c GO annotations for biological processes, molecular functions, and cellular components of upregulated proteins in CoCl2 + R28 cells treated with exosomes, compared with those of R28 cells damaged by CoCl2. d GO annotations for biological processes, molecular functions, and cellular components of downregulated proteins in CoCl2 + R28 cells treated with exosomes, compared with those of R28 cells damaged by CoCl2 (false discovery rate ≤ 0.05)

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