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Fig. 1 | Stem Cell Research & Therapy

Fig. 1

From: Epigenetic silencing of KLF2 by long non-coding RNA SNHG1 inhibits periodontal ligament stem cell osteogenesis differentiation

Fig. 1

SNHG1 was downregulated and KLF2 was upregulated in osteogenic differentiated PDLSCs. A Flow cytometric analysis showing positive expression of CD73 and CD90 and negative expression of CD31 and CD34 in PDLSCs. B Multiple differentiation of PDLSCs. Osteogenic differentiation ability of PDLSCs assayed by ALP staining (a) and alizarin red staining (b). Adipogenic differentiation ability of PDLSCs assayed by oil red O staining (c). Chondrogenic differentiation ability of PDLSCs assayed by alcian blue staining (d). C Relative ALP activity was measured at day 3, 7, and 14. D, E The mRNA expression levels of SNHG1 (D) and KLF2 (E) were analyzed by qRT-PCR at day 3, 7, and 14, with GAPDH as a control. *p < 0.05; **p < 0.01 versus day 0

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Stem Cell Research & Therapy

ISSN: 1757-6512