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Fig. 6 | Stem Cell Research & Therapy

Fig. 6

From: HSPB7 regulates osteogenic differentiation of human adipose derived stem cells via ERK signaling pathway

Fig. 6

HSPB7 knockdown promoted bone formation of hASCs in vivo. a HSPB7 knockdown promoted bone formation capacity of hASCs in vivo, as determined by HE staining (HE) and Masson’s trichrome staining (Masson). b HSPB7 overexpression inhibited bone formation capacity of hASCs. c Quantitative measurements of bone-like tissue showed the area of bone-like tissue was significantly increased in HSPB7 knockdown hASCs but decreased in HSPB7 overexpression hASCs. Black arrows indicate new bone-like tissue. Scale bar = 50 μm. Data are presented as the mean ± SD (**P < 0.01, compared with shNC or NC)

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