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Fig. 2 | Stem Cell Research & Therapy

Fig. 2

From: Epidrugs: novel epigenetic regulators that open a new window for targeting osteoblast differentiation

Fig. 2

Schematic presentation of epidrugs’ effect on the promotion of osteogenesis. After treatment of MSCs with epidrugs, there is a decrease in the epigenetic marks responsible for the silencing genes (DNA methylation, histone methylation) and an increase in gene-activating epigenetic marks (histone acetylation) in osteogenic genes, which result in promotion of osteogenesis

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Stem Cell Research & Therapy

ISSN: 1757-6512