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Fig. 3 | Stem Cell Research & Therapy

Fig. 3

From: Epidermal stem cell-derived exosomes promote skin regeneration by downregulating transforming growth factor-β1 in wound healing

Fig. 3

EPSC-Exos improved the regeneration level of skin appendages and the collagen distribution on wound healing of the rats. a Haematoxylin and eosin and Masson staining of the wound healing tissues. Scale bar = 100 μm. b Number of skin appendages (hair follicles and sebaceous glands) in the healing tissue according to haematoxylin and eosin staining. c, d The proportion of myofibers (red) and collagen fibres (blue) in the healing tissue, according to Masson staining. eg Collagen I mRNA, collagen III mRNA and collagen I/collagen III levels in the healing tissue. *P < 0.05; **P < 0.01; ***P < 0.001; mean ± SD; n = 5. Ctrl, control; EGF, epidermal growth factor; EPSC-Exos, epidermal stem cell-derived exosomes

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