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Fig. 4 | Stem Cell Research & Therapy

Fig. 4

From: Epidermal stem cell-derived exosomes promote skin regeneration by downregulating transforming growth factor-β1 in wound healing

Fig. 4

EPSC-Exos promote nerve and vessel regeneration on wound healing of rats. a Immunohistochemistry of the wound healing tissues. Scale bar = 200 μm. b–d The proportion of CD31+ (vessel), nestin+ (nerve) and Ki67+ (cell proliferation) expressions in the healing tissue according to immunohistochemistry. *P < 0.05; **P < 0.01; ***P < 0.001; mean ± SD; n = 5. Ctrl, control; EGF, epidermal growth factor; EPSC-Exos, epidermal stem cell-derived exosomes; CD31, platelet endothelial cell adhesion molecule-1; IHC, immunohistochemical staining

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Stem Cell Research & Therapy

ISSN: 1757-6512