Skip to main content
Fig. 6 | Stem Cell Research & Therapy

Fig. 6

From: Human adipose mesenchymal stem cells modulate myeloid cells toward an anti-inflammatory and reparative phenotype: role of IL-6 and PGE2

Fig. 6

CD14/CD1a surface expression and phagocytic capacity of ASC-educated mDCs are modulated by IL-6 and PGE2. a Dot plots showing the surface expression of CD14/CD1a, in monocyte-derived mDCs in the presence or absence of ASCs and modulated by IL-6 or PGE2 inhibitors, measured by flow cytometry (n = 3). b Histograms show the phagocytosis levels of S. aureus particles by monocyte-derived mDCs, in the presence or absence of ASCs, and modulated by IL-6 or PGE2 inhibitors, measured by flow cytometry. c Graphs showing the average percentage of CD14+/CD1a− ± SEM (left) and the average increase of the percentage of phagocytic cells ± SEM (right) (n = 3). IgG1 was the negative control for αIL-6, and ethanol was added as an indomethacin carrier. *p < 0.05. ASC, adipose-derived mesenchymal stem cell; CD, cluster of differentiation; EtOH, ethanol; IgG, immunoglobulin G; Indo, indomethacin; IL, interleukin; mDC, mature dendritic cell; PGE2, prostaglandin E2; S. aureus, Staphylococcus aureus

Back to article page

Stem Cell Research & Therapy

ISSN: 1757-6512