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Fig. 4 | Stem Cell Research & Therapy

Fig. 4

From: miRNA-126-3p carried by human umbilical cord mesenchymal stem cell enhances endothelial function through exosome-mediated mechanisms in vitro and attenuates vein graft neointimal formation in vivo

Fig. 4

The role and mechanisms of miRNA-126-3p-hucMSCs-exosomes in the promotion of HUVECs proliferation, migration, and tube formation. a The morphology of hucMSCs-exosomes. b Western blotting analysis of exosome markers. c DiI-labeled hucMSCs-exosomes (red) could be internalized by DAPI-labeled HUVECs (blue). d The expression of miRNA-126-3p in exosomes derived from hucMSCs and GFP-hucMSCs and miRNA-126-3p-hucMSCs. e Quantification of the proliferation rates of HUVECs. f Quantification of the migration area of HUVECs. g Quantification of the migrated cell numbers of HUVECs. Quantification of the h tube length and tubes numbers (i) of HUVECs

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Stem Cell Research & Therapy

ISSN: 1757-6512