Table 1 Demographic and clinical data of the investigated case-parent trio, the extended family, and the unrelated healthy control individual
Subject | Sex | Age | Medical history | Code |
|---|---|---|---|---|
Father | M | 59 | No psychiatric treatment or other major somatic disorders. | iPSC-SZ-HU-FA 1 |
Mother | F | 55 | No psychiatric treatment or other major somatic disorders. | iPSC-SZ-HU-MO 1 and 2 |
Proband (son) | M | 24 | Diagnosed with schizophrenia at the age of 17. During the past 10 years had 3 hospitalizations, receives clozapine treatment. Predominantly negative symptoms, as measured by PANSS. | iPSC-SZ-HU-PROB 1 and 2 |
Unaffected older sibling | M | 28 | No psychiatric treatment or other major somatic disorders. | – |
Younger sibling | F | 21 | Diagnosed with bipolar affective disorder at age of 18 after suicidal attempt. Receives lithium and olanzapine treatment. | – |