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Table 1 Baseline characteristics of enrolled patients

From: Autologous peripheral blood-derived stem cells transplantation for treatment of no-option angiitis-induced critical limb ischemia: 10-year management experience

Characteristics

Total

PCCs (82)

PBMNCs (78)

P

Age, years

41.2 (11.2)

40.6 (10.5)

41.8 (11.8)

.610

Male, n (%)

157 (98.1)

80 (97.6)

77 (96.3)

.990

BMI, kg/m2

23.2 (3.7)

23.5 (3.5)

22.9 (3.8)

.820

Etiology

 TAO, n (%)

155 (96.9)

79 (96.3)

76 (97.4)

1.000

 Eosinophilia, n (%)

1 (0.63)

0 (0)

1 (1.30)

.487

 SLE, n (%)

3 (1.88)

2 (2.4)

1 (1.3)

1.000

 Erythema nodosum, n (%)

1 (0.63)

1 (1.2)

0 (0)

1.000

Comorbidities

 Smoking, n (%)

145 (90.6)

72 (87.8)

73 (93.6)

.210

 Hypertension, n (%)

8 (5.0)

5 (6.1)

3 (3.8)

.720

 Type II diabetes mellitus, n (%)

8 (5.0)

4 (4.9)

4 (5.1)

.990

 Hyperlipidemia, n (%)

11 (6.88)

7 (8.5)

4 (5.1)

.394

 Coronary artery disease, n (%)

3 (1.88)

2 (2.4)

1 (1.3)

.990

Treated limbs

 Upper/lower extremity, n

5/155

3/79

2/76

.990

 Right/left, n

86/74

44/38

42/36

.989

 Ulcer only, n (%)

75 (46.9)

34 (41.5)

41 (52.6)

.160

 Gangrene, n (%)

70 (43.8)

37 (4.1)

33 (42.3)

.720

Rutherford class

 4, n (%)

15 (18.3)

11 (13.4)

4 (5.1)

.720

 5, n (%)

145 (90.6)

71 (86.6)

74 (94.9)

.720

Medication history

 Aspirin, n (%)

134 (83.8)

66 (80.5)

68 (87.2)

.251

 Clopidogrel, n (%)

18 (11.3)

10 (12.2)

8 (11.2)

.698

 Cilostazol, n (%)

61 (38.1)

32 (39.0)

29 (37.2)

.810

 Prostaglandins, n (%)

124 (77.5)

61 (74.4)

63 (80.8)

.334

 Warfarin, n (%)

6 (3.8)

4 (4.9)

2 (2.6)

.682

 Rivaroxaban, n (%)

5 (3.1)

2 (2.4)

3 (3.8)

.676

Surgical history

 Bypass, n (%)

18 (11.3)

11 (13.4)

7 (9.0)

.374

 Endarterectomy, n (%)

5 (3.1)

3 (3.7)

2 (2.6)

1.000

 PTA, n (%)

42 (26.3)

20 (24.2)

22 (28.2)

.584

 Stenting, n (%)

16 (10.0)

8 (9.8)

8 (10.3)

.916

 Thrombolysis, n (%)

52 (32.5)

28 (34.1)

24 (30.8)

.648

 Sympathectomy, n (%)

7 (4.4)

2 (2.4)

5 (6.4)

.268

 Surgical thrombectomy, n (%)

22 (13.8)

12 (14.6)

10 (12.8)

.739

 Excimer laser thrombectomy, n (%)

7 (4.4)

2 (2.4)

5 (6.4)

.268

  1. PCCs purified CD34+ cells, PBMNCs peripheral blood mononuclear cells, BMI body mass index, TAO thromboangiitis obliterans, SLE systemic lupus erythematosus, PTA percutaneous transluminal angioplasty