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Fig. 4 | Stem Cell Research & Therapy

Fig. 4

From: Human placenta-derived mesenchymal stem cells stimulate ovarian function via miR-145 and bone morphogenetic protein signaling in aged rats

Fig. 4

Changes in circulating miRNA levels involved in the ovarian reserve and function after hPD-MSC therapy. a, b Levels of circulating miRNAs in serum were measured by qRT-PCR. The expression of miR-21-5p, miR-132-3p, and miR-212-3p, related to the ovarian reserve, was significantly increased, whereas the expression of miR-16-5p, miR-34a-5p, miR-145-5p, and miR-191-5p, related to the inhibition of folliculogenesis, was substantially suppressed. The results are presented as the mean ± SEM. Single and double asterisks, * and **, represent statistical significance at p < 0.01 and p < 0.05, respectively

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Stem Cell Research & Therapy

ISSN: 1757-6512