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Fig. 1 | Stem Cell Research & Therapy

Fig. 1

From: Bone marrow mesenchymal stem cell-derived exosomes promote plasminogen activator inhibitor 1 expression in vascular cells in the local microenvironment during rabbit osteonecrosis of the femoral head

Fig. 1

Representative micro-CT and Masson staining images of GC-induced rabbit ONFH. a Reconstructed coronal, sagittal, and axial images of femoral head within the control and experimental (GC) groups. In the control group, the trabecular bone showed a better structural integrity, whereas in the experimental (GC) group, the trabecular bone was sparse and relatively thin. b Quantitative CT analysis. Quantitative analysis showed that BV/TV, Tb.Th were all significantly lower in the experimental (GC) group compared to that of the control group. Asterisks (*) indicate significant differences (p < 0.05) and **p < 0.01. The results are presented as the means ± s.e.m. c Histological morphology of the bone marrow in GC-induced ONFH by Masson’s trichrome staining. The bone marrow was replaced by degenerated hypertrophic adipocytes and necrotic tissues in the experimental (GC) group. Hyperplasic and thickened small vessels endothelium where also found, as well as empty lacunae in the GC group. Magnification: ×200. Black arrows indicate the intraosseous vessels

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