Fig. 2From: Bone marrow mesenchymal stem cell-derived exosomes promote plasminogen activator inhibitor 1 expression in vascular cells in the local microenvironment during rabbit osteonecrosis of the femoral headElevation of PAI-1 in GC-induced rabbit ONFH in vivo. a Organ and bone tissue of the lower extremities in rabbit were tested (n = 5). b Expression of PAI-1 of organs was significantly increased following GC treatment, as shown by qRT-PCR. c Bone tissue from the lower extremities and blood samples presented a significant increase of PAI-1 expression following GC treatment, as shown by qRT-PCR. d PAI-1 concentrations in the femoral head, knee, ankle, and blood samples were remarkably increased after the GC treatment, as shown by ELISA. e Representative immunohistochemical staining of PAI-1 in samples of the femoral head from the control and GC-induced experimental groups. Magnification: ×40. Enlarged images shown in the lower right corner at ×100. Asterisks (*) indicate significant differences (p < 0.05) and **p < 0.01. The results are presented as the means ± s.e.mBack to article page