Fig. 1

hPMSCs relieves d-gal-triggered CD4⁺ T cells senescence in mice. a The scheme of the experimental design. b–d The expression of ROS in CD4⁺ T cells. e–g The antioxidant enzyme activity of SOD, CAT, and GSH-Px in CD4⁺ T cells. h, i The percentages of SA-β-gal-positive CD4⁺ T cells are shown (bar = 10 μm). j, k The expressions of senescent markers P16 and P21 in CD4⁺ T cells. l The mRNA expressions of IL-6 and OPN in CD4⁺ T cells. Data represent the mean scores ± SEM of at least three independent experiments. *p < 0.05, **p < 0.01 (n = 10 animals per group)