Fig. 3
From: Mesenchymal stem cells: amazing remedies for bone and cartilage defects
Mechanisms of MSC-mediated cartilage repair. The figure was designed using the web-based tool BioRender. Mesenchymal stem cells (MSCs) contribute to cartilage regeneration by several mechanisms including response to inflammation condition and differentiation through production of a variety of mediators. Matrix metalloproteinase (MMP), tissue inhibitors of metalloproteinases (TIMP), tumor necrosis factor alpha (TNF-α), prostaglandin E2 (PGE2), interleukin (IL), hepatocyte growth factor (HGF), thrombospondin (TSP2)