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Fig. 5 | Stem Cell Research & Therapy

Fig. 5

From: Microenvironmental changes induced by placenta-derived mesenchymal stem cells restore ovarian function in ovariectomized rats via activation of the PI3K-FOXO3 pathway

Fig. 5

Serum hormone levels in the excised ovaries of rats after coculture with PD-MSCs. a Schematic illustration of how the ex vivo coculture system was established. One half of the rat ovary was cultured with or without PD-MSCs for 24, 48, and 72 h. The levels of b AMH and c FSH in the supernatants at 24, 48, and 72 h after PD-MSC coculture were analyzed by enzyme-linked immunosorbent assay (mean ± SE). All experiments were performed in triplicate. Significance at p < 0.05 is indicated by an asterisk (*) for NTx vs. others and a number sign (#) for DTx vs. TTx

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