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Fig. 2 | Stem Cell Research & Therapy

Fig. 2

From: Bone marrow mesenchymal stem cell-derived exosomes promote rotator cuff tendon-bone healing by promoting angiogenesis and regulating M1 macrophages in rats

Fig. 2

Functional effects of BMSC-Exos on HUVECs. a, b BMSC-Exos significantly promoted the proliferation of HUVECs, as demonstrated by the Cell Counting Kit-8 (CCK-8) and EdU assays. Scar bar 100 μm. c BMSC-Exos significantly promoted the migration of HUVECs as determined by the transwell assay at 24 h. Scar bar 100 μm. d Quantitative analysis of the transwell assay. e BMSC-Exos significantly promoted the mobility of HUVECs as determined by the scratch wound assay. Scar bar 100 μm. f Quantitative analysis of the scratch wound assay. g BMSC-Exos significantly enhanced the tube formation ability at 6 h, as determined by the tube formation assay. Scar bar 250 μm. h, i Quantitative analysis of the tube formation assay. Each experiment was independently repeated three times (*p < 0.05; **p < 0.01; ***p < 0.001)

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Stem Cell Research & Therapy

ISSN: 1757-6512