Fig. 2
Transplanted MSCs promoted cutaneous wound healing while underwent apoptosis. a The schematic graph shows the protocol of establishment and treatment for mouse skin wound models. b Representative photographs of cutaneous wounds in different groups at different time points during the wound healing procedure. c Quantification of the wound healing rate. d Quantification of the body weight. e Representative images of the H&E staining of the skin samples. Scale bar, 1 mm in low-magnification images, 500 μm in high-magnification images. f Representative images of the Masson staining of the skin samples. Scale bar, 1 mm in low-magnification images, 500 μm in high-magnification images. g Representative images and quantification of the cytokeratin 14 expression in the skin samples. Scale bar, 100 μm. h Representative images of TUNEL staining of skin tissue. Scale bar, 100 μm in low-magnification images, 50 μm in high-magnification images. n = 6 per group. Data shown as mean ± SD. *P < 0.05; **P < 0.01; ***P < 0.001; NS, not significant. PBS, phosphate-buffered saline; Gel, PF-127 gel; Gel+MSCs, MSCs embedded in PF-127; MSCsPKH26, MSCs labeled with PKH26