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Fig. 1 | Stem Cell Research & Therapy

Fig. 1

From: Exosomes from adipose tissue-derived mesenchymal stem cells ameliorate histone-induced acute lung injury by activating the PI3K/Akt pathway in endothelial cells

Fig. 1

Effects of histones with or without ADSC administration in mice. a Representative pictures of the lung CT scan 1 h after injection of 75 mg/kg histones. b Kaplan-Meier survival curves showing survival in the saline+histones group and the ADSCs+histones group. N = 8 in each group. *p = 0.0256 vs. saline+histones group. c In vivo pulmonary vascular permeability assay measured by Evans Blue dye. N = 5 in each group. **p < 0.01 vs. control group, p < 0.05 vs. saline+histones group. d Representative photomicrographs of lung sections with H&E staining 6 h after injections of ADSCs and histones. Scale Bar, 50 μm

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