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Fig. 6 | Stem Cell Research & Therapy

Fig. 6

From: Extracellular vesicles from hydroxycamptothecin primed umbilical cord stem cells enhance anti-adhesion potential for treatment of tendon injury

Fig. 6

The improved anti-adhesion effect of HCPT-EVs was attributed to activation of the ERS pathway. a Representative WB images of GRP78, CHOP, Bax, and Bcl-2. b BCA was applied to determine the total protein concentration of EVs. Rat fibroblasts were treated with salubrinal (10 μM) for 1 h before incubation with Unprimed EVs or HCPT-EVs (100 μg/mL) in the presence of TGF-β1 (2 ng/ml) for 48 h. c Representative WB images of COL III and α-SMA. d, e Semiquantitative analysis of COL III and α-SMA. *P < 0.05, **P < 0.01, ***P < 0.001; ns, not significant

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