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Fig. 6 | Stem Cell Research & Therapy

Fig. 6

From: Human levator veli palatini muscle: a novel source of mesenchymal stromal cells for use in the rehabilitation of patients with congenital craniofacial malformations

Fig. 6

Histological analysis of bone neoformation at 30 days post-surgery. Rat defect (right side) seeded with LVPMDSC associated with CellCeram™, revealing higher bone neoformation in different magnifications—× 25 and × 100 (a, c), when compared with the defect (left side) where only CellCeram™ was applied (b, d). In a and c, we observe greater bone neoformation (blue arrows) intermixed with granulation tissue with few remnants of CellCeram™ (yellow arrow), while in b and d the defect is filled with loose connective tissue exhibiting chronic inflammatory infiltrate (II), intermingled with remnants of CellCeram™ (yellow arrows) and only a small number of trabeculae of recently formed bone. NB, naive bone; CD, critical defect; II, inflammatory infiltrate

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Stem Cell Research & Therapy

ISSN: 1757-6512