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Fig. 7 | Stem Cell Research & Therapy

Fig. 7

From: MiR-218 affects hypertrophic differentiation of human mesenchymal stromal cells during chondrogenesis via targeting RUNX2, MEF2C, and COL10A1

Fig. 7

Gain of miR-218 at the start of chondrogenic differentiation leads to increased accumulation of cytosolic β-catenin. MSC (N = 4 donors) were transfected with miR-218 (gray), or with a control non-targeting miR (NC, black) mimic at day 0, subjected to chondrogenic differentiation for 28 days, and β-catenin accumulation (a) was assessed by Western blot analysis at day 28. b Semi-quantitative analysis of WB images; α-tubulin was used as a loading control; mean values ± SD are shown; N = 4; **p ≤ 0.01, two-tailed t test

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