Table 3 Significantly enriched KEGG pathways associated with the predicted target genes for miR-218 (selected categories for “signal transduction,” “signaling molecules and interaction,” and “glycan biosynthesis and metabolism” identifiers)

PI3K-Akt signaling pathway

106

3.7E−3

MAPK signaling pathway

86

3.5E−4

cAMP signaling pathway

72

1.2E−4

Calcium signaling pathway

67

7.9E−5

Hippo signaling pathway

56

4.3E−4

AMPK signaling pathway

49

1.6E−4

Signaling pathways regulating pluripotency of stem cells

45

2.9E−2

Wnt signaling pathway

43

5.3E−2

Thyroid hormone signaling pathway

40

1.1E−2

HIF-1 signaling pathway

38

1.1E−3

TNF signaling pathway

35

4.3E−2

NF-kappa B signaling pathway

30

3.3E−2

ECM-receptor interaction

28

8.6E−2

mTOR signaling pathway

27

4.3E−4

TGF-beta signaling pathway

27

9.3E−2

Hedgehog signaling pathway

11

9.3E−2

Glycosaminoglycan biosynthesis - chondroitin sulfate/dermatan sulfate

9

8.6E−2