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Fig. 3 | Stem Cell Research & Therapy

Fig. 3

From: Human embryonic stem cell-derived extracellular vesicles alleviate retinal degeneration by upregulating Oct4 to promote retinal Müller cell retrodifferentiation via HSP90

Fig. 3

hESEVs promote the retrodifferentiation of Müller cells into retinal progenitor cells in vitro. Müller cells were treated with DiI labeled-hESEVs. Immunofluorescence was used to observe DiI labeled-hESEVs: green indicates DiI labeled-hESEVs and blue indicates DAPI-labeled nuclear DNA of Müller cells (bar = 25 μm) (a). The fluorescence intensities of Vimentin (b) and CHX10 (c) in retinal Müller cells at the 48th hours of treatment were assessed by immunofluorescence; hESEVs, human embryonic stem extracellular vesicles

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Stem Cell Research & Therapy

ISSN: 1757-6512