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Fig. 6 | Stem Cell Research & Therapy

Fig. 6

From: Differential expression profiles of long noncoding RNAs and mRNAs in human bone marrow mesenchymal stem cells after exposure to a high dosage of dexamethasone

Fig. 6

The differential expression profiles of the mRNAs in Dex-induced apoptotic hBMSCs and bioinformatics analysis. a A heat map of the distinct mRNAs based on the microarray assay. b A volcano plot of the distinct mRNAs based on thee microarray assay. Red dots represent upregulated mRNAs, and green dots represent downregulated mRNAs with statistical significance (fold change ≥ 2, P value < 0.05). Bubble maps of the GO enrichment analysis for c biological processes, d molecular functions, and e cellular components. f A bubble map of the pathway enrichment analysis showing the top 30 signaling pathways with significant changes. Notes: D, dexamethasone-induced group (n = 3); C, control group (n = 3); Dex, dexamethasone; hBMSCs, human bone marrow mesenchymal stem cells; GO, gene ontology; KEGG, Kyoto Encyclopedia of Genes and Genomes pathway analysis

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