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Table 1 GSK-J4 treatment prevents unilateral and bilateral craniosynostosis in Twist-1del/+ mice

From: Pharmacological targeting of KDM6A and KDM6B, as a novel therapeutic strategy for treating craniosynostosis in Saethre-Chotzen syndrome

 

DMSO control

2 μM GSK-J4

Open coronal sutures

1

4

Unilateral coronal craniosynostosis

2

1

Bilateral coronal craniosynostosis

3

0

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Stem Cell Research & Therapy

ISSN: 1757-6512