Fig. 2

Correlation of gene expression and differentially methylated regions (DMRs) between adipogenic and myogenic precursors. a The links of DMRs and detected genes in adipogenic and myogenic precursors. b Scatterplot of DMR-linked genes, integrating significant change in DNA methylation (x-axis) and gene expression (y-axis). DMRs with ±2-fold changes are yellow, red, blue, and green colored dependent on the methylation and expression status, whereas DMRs with no changes in gene expression are gray colored. Column graph (right) indicating the percentage of hypo- and hyper-methylated DMRs showing up or down gene regulation in myogenic precursors compared with that in adipogenic precursors. c Dot plots of gene expression fold changes between adipogenic and myogenic precursors for hyper-methylated (red circles) and hypo-methylated (blue circles) regions. Black horizontal lines in the boxplots indicated median fold change.^*P < 0.05, NS, no significance