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Fig. 2 | Stem Cell Research & Therapy

Fig. 2

From: circAKT3 positively regulates osteogenic differentiation of human dental pulp stromal cells via miR-206/CX43 axis

Fig. 2

Microarray profiling showing differentially-expressed circRNAs during hDPSC osteogenesis. a The heatmap of the overall expression profiles of circRNAs during hDPSC osteogenesis for 0D and 14D (OM 0D vs OM 14D). b qRT-PCR of ten circRNAs for the validation of circRNA microarray results. c The top significant Gene Ontology (GO) terms of genes upregulated in OM 14D than OM 0D. d Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway analysis of parental mRNAs showed the top 12 mRNA-enriched pathways. *p < 0.05 and **p < 0.01 compared with OM 0D. hDPSCs were harvested in two groups with three biological replicates

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