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Fig. 5 | Stem Cell Research & Therapy

Fig. 5

From: Human umbilical cord mesenchymal stem cell-derived exosomal miR-27b attenuates subretinal fibrosis via suppressing epithelial–mesenchymal transition by targeting HOXC6

Fig. 5

Inhibitory effect of hucMSC-Exo on TGF-β2-treated EMT in ARPE19 cells. a Immunofluorescence staining of Vimentin, ZO-1, and a-SMA expression in ARPE19 cells treated with or without 100 μg/mL hucMSC-Exo; the nuclei were stained with DAPI. b Extracted total protein was loaded and analyzed by Western blot analysis. The relative protein expression was quantified. The data represent the average of three independent experiments. Statistics are presented as means ± SD. *P < 0.05, **P < 0.01, ***P < 0.001

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