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Fig. 2 | Stem Cell Research & Therapy

Fig. 2

From: Glucocorticoid guides mobilization of bone marrow stem/progenitor cells via FPR and CXCR4 coupling

Fig. 2

Glucocorticoid increased the FPR expression of bone marrow-derived stem/progenitor cell subsets via glucocorticoid receptor. a GC enhanced FPR mRNA expression in MSCs. *P < 0.05, **P < 0.01 vs. the control group, #P < 0.05 vs. the 75 ng/ml group. b GC enhanced the FPR mRNA expression in EPCs. *P < 0.05, **P < 0.01 vs. the control group, #P < 0.05 vs. the 75 ng/ml and 100 ng/ml groups. c RU486 inhibited GC-induced FPR mRNA expression in MSCs. **P < 0.01 vs. the control group, ##P < 0.01 vs. the 75 ng/ml group. d RU486 inhibited GC-induced FPR mRNA expression in EPCs. *P < 0.05, **P < 0.01 vs. the control group, ##P < 0.01 vs. the 75 ng/ml group. e, g FPR protein expression in MSCs. *P < 0.05, **P < 0.01 vs. the 0 ng/ml group. Control: the negative control. #P < 0.05 vs. the 75 ng/ml group. f, h FPR protein expression in EPCs. *P < 0.05, **P < 0.01 vs. the 0 ng/ml group. Control: the negative control. #P < 0.05, ##P < 0.01 vs. the 75 ng/ml group. MSCs, mesenchymal stem cells; EPCs, endothelial progenitor cells; GC, glucocorticoid; FPR, formyl peptide receptor. Data are mean ± SD of six representative observations

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