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Fig. 1 | Stem Cell Research & Therapy

Fig. 1

From: LncRNA NORAD promotes bone marrow stem cell differentiation and proliferation by targeting miR-26a-5p in steroid-induced osteonecrosis of the femoral head

Fig. 1

LncRNA NORAD expression was downregulated in SONFH tissues and Dex-treated hBMSCs, and treatment of Dex inhibited proliferation and the OPG/RANK/RANKL pathway in hBMSCs. a The NORAD expression in bone marrow samples from patients with SONFH (n = 20) and femoral neck fracture (control, n = 20) was detected by RT-qPCR. b The NORAD expression in different concentration of Dex-treated hBMSCs was detected by RT-qPCR. c The proliferation ability of hBMSCs was measured by the CCK-8 assay. d–f The mRNA expression of OPG (d), RANK (e), and RANKL (f) was detected by RT-qPCR. P < 0.01 and P < 0.05 compared with the control group

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Stem Cell Research & Therapy

ISSN: 1757-6512