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Fig. 3 | Stem Cell Research & Therapy

Fig. 3

From: LncRNA NORAD promotes bone marrow stem cell differentiation and proliferation by targeting miR-26a-5p in steroid-induced osteonecrosis of the femoral head

Fig. 3

Knockdown of NORAD aggravated Dex-induced inhibition of proliferation and differentiation, and promotion of apoptosis in hBMSCs. a The NORAD expression in hBMSCs was detected by RT-qPCR. b The bands of RUNX2, OPG, RANK, and RANKL protein was detected by western blot. cf The protein expression of RUNX2 (c), OPG (d), RANK (e), and RANKL (f) was detected by western blot. g The proliferation ability of hBMSCs was measured by the CCK-8 assay. h The flow cytometry was used to detect apoptosis in hBMSCs. **P < 0.01 compared with control group, ##P < 0.01 and #P < 0.05 compared with Dex and si-NC group, &&P < 0.01 and &P < 0.05 compared with Dex+si-NC group

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