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Fig. 2 | Stem Cell Research & Therapy

Fig. 2

From: Radial extracorporeal shockwave promotes subchondral bone stem/progenitor cell self-renewal by activating YAP/TAZ and facilitates cartilage repair in vivo

Fig. 2

General flow diagram of the experiment. a Isolation, cultivation, and characterization of SCB-SPCs. b Optimization of r-ESW parameters for the self-renewal of SCB-SPCs. c The influences of the optimized parameters on the proliferation, apoptosis, and multidifferentiation of SCB-SPCs. d The in vivo therapeutic effects of SCB-SPCs pretreated by r-ESW via an osteochondral lesion model. e The underlying mechanisms involved in the mechanotransduction process mediated by r-ESW were explored. SCB-SPCs, subchondral bone stem/progenitor cells. r-ESW, radial extracorporeal shockwave

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