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Fig. 3 | Stem Cell Research & Therapy

Fig. 3

From: Radial extracorporeal shockwave promotes subchondral bone stem/progenitor cell self-renewal by activating YAP/TAZ and facilitates cartilage repair in vivo

Fig. 3

Optimization of radial shockwave parameters. a Representative images of CFU-F stained by crystal violet after gradient doses of radial shockwave stimulation. b Quantitative comparison of colony numbers in each group based on CFU-F results. The combined analysis suggests that radial shockwave promotes the self-renewal of SCB-SPCs in a dose-dependent manner (n = 5, with each 3 technical repeats). c The optimized parameters of radial shockwave significantly enhance the proliferation of SCB-SPCs (n = 5, with each 3 technical repeats). d Compared with the control group, the optimized radial shockwave stimulation had no significant influence on the apoptosis of SCB-SPCs (n = 5, with each 3 technical repeats). *p < 0.05, ***p < 0.001, ns, not significant. SCB-SPCs, subchondral bone stem/progenitor cells

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Stem Cell Research & Therapy

ISSN: 1757-6512